Heat Shock Proteins (HSP) in Translational Neuroscience
نویسندگان
چکیده
The book Heat Shock Proteins (HSP) in Translational Neuroscience Volume 27 is the concise collection of articles focused to develop efficient therapies aimed at combatting various types neurodegenerative diseases. Using an integrative approach, contributors provide most comprehensive review on role HSP signaling pathways relevant several To enhance knowledge diseases, this reviews current progress our understanding diseases including glioblastoma, neuro-oncology, Alzheimer’s and central nervous system.
منابع مشابه
HDAC Inhibitors and Heat Shock Proteins (Hsps)
Epigenetic alterations, including DNA acetylation, hypermethylation and hypomethylation, and the associated transcriptional changes of the affected genes are central to the evolution and progression of various human cancers, including pancreatic cancer. Cancer-associated epigenetic alterations are attractive therapeutic targets because such epigenetic alterations, unlike genetic changes, are po...
متن کاملHeat shock and the heat shock proteins.
As all biologists appreciate, there is constant interaction between life and the environment, and temperature plays a critical role. It establishes distribution limits, it affects rates of function as well as the survival of organisms. Notoriously sensitive to temperature is plant growth. Critical steps in plant life such as germination, flowering and breaking of dormancy can be manipulated by ...
متن کاملSpecies-specific collaboration of heat shock proteins (Hsp) 70 and 100 in thermotolerance and protein disaggregation.
Yeast Hsp104 and its bacterial homolog, ClpB, are Clp/Hsp100 molecular chaperones and AAA+ ATPases. Hsp104 and ClpB collaborate with the Hsp70 and DnaK chaperone systems, respectively, to retrieve and reactivate stress-denatured proteins from aggregates. The action of Hsp104 and ClpB in promoting cell survival following heat stress is species-specific: Hsp104 cannot function in bacteria and Clp...
متن کاملHeat shock proteins.
The enhanced synthesis of a few proteins immediately after subjecting cells to a stress such as heat shock was first reported for drosophila cells in 1974 (l), and the universality of the response from bacteria to human was recognized shortly thereafter (reviewed in Ref. 2). In the ensuing 16 years, a vast literature has accumulated that describes a wide variety of events in a cell’s response t...
متن کاملThe heat-shock proteins.
PERSPECTIVES ANDUMMARY .............................................................. 632 HSP110 .................................................................................................. 634 THE HSP 90 FAMILY .............................................................................. 634 Biochemical Analysis ..............................................................................
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ژورنال
عنوان ژورنال: Heat shock proteins
سال: 2023
ISSN: ['1877-1254', '1877-1246']
DOI: https://doi.org/10.25259/hsp-27